Creatine may normalize homocysteine levels. What are the consequences of having to make your own creatine rather than relying on dietary sources?

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This is the 11th in a 12-video series exploring stroke risk. If you missed the last few, see
Vegetarians and Stroke Risk Factors—Vitamin B12 & Homocysteine? ( and How to Test for Functional Vitamin B12 Deficiency (

This whole creatine angle was something new to me. I had long worried about homocysteine levels being too high among those getting inadequate B12 intake, but didn’t realize there was potentially another potential mechanism for bring it down other than vitamin B intake. Let’s see if it pans out in my final video of the series: The Efficacy and Safety of Creatine for High Homocysteine (

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Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution!
-Michael Greger, MD FACLM

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